Therapeutic Applications of Squalene - A Review
Therapeutic Applications of Squalene - A Review
Date
2012
Authors
Gopakumar, K.
Journal Title
Journal ISSN
Volume Title
Publisher
Society of Fisheries Technologists (India)Cochin
Abstract
The article gives an overview of squalene, a
naturally occurring antioxidant and its medical
applications for human beings. The sources and
properties of squalene and its occurrence in human
beings are discussed. Deep sea sharks belonging to
the family squalidae are the richest source of
squalene. Squalene’s cytoprotective activity, antioxidant
property, cholesterol lowering property and
effect of squalene on testosterone level, obesity and
high blood pressure are detailed. Rapid transdermal
absorption, creation of moisture barrier, high
spreadability, non-greasy texture and antibacterial
properties of squalene make it an excellent skin
protector and finds application against eczema and
in anti-aging and wrinkle protecting cosmetics.
Being an adjuvant in vaccines, it stimulates the
immune system and increases response to vaccines.
Being a safe and naturally occurring antioxidant, its
application for human health is very important. Its
availability in nature viz., from deep sea shark liver
and olive oil cannot meet the growing demand of
industry. Synthesis of squalene by organic hemisynthesis
should be explored to meet the demand
Description
Keywords
Squalene, deep sea shark, antioxidant, cholesterol, cytoprotective activity
Citation
Fishery Techn 49(1):1-9