Hypolipidaemic and anti-oxidative potential of encapsulated herb (Terminalia arjuna) added vanilla chocolatemilk in high cholesterol fed rats

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dc.contributor.authorSawale, P.D.
dc.contributor.authorPothuraju, R.
dc.contributor.authorHussain, S.A.
dc.contributor.authorAnuj, K.
dc.contributor.authorKapila, S.
dc.contributor.authorPatil, G.R.
dc.date.accessioned2016-10-28T09:08:07Z
dc.date.available2016-10-28T09:08:07Z
dc.date.issued2016
dc.description.abstractAtherosclerosis is associated with coronary artery disease and occurs in developing as well as developed countries. In the present investigation, hypolipidaemic and anti-oxidative properties of encapsulated herb (Terminalia arjuna, 1.8%) added vanilla chocolate dairy drink was evaluated in high cholesterol fedWistar rats for 60 days. At the end of the experimental period, a significant decrease in the body weight gain by rats receiving the encapsulated herb extract was noted as compared to high cholesterol fed rats. Administration of microencapsulated herb showed a statistically significant decrease in organweights (epididymal fat and liver). Moreover, a significant decrease in serum lipids such as triglycerides, total cholesterol, low-density lipoprotein cholesterol, very-low-density lipoprotein cholesterol and atherogenic indexwas observed with encapsulated Terminalia arjuna extract in high cholesterol fed group. Increases in reduced glutathione and decreases in TBARS levels were also reported in both liver and red blood cell lysates with encapsulated herb supplementation. The results demonstrated that the bioactive components (phytosterols, flavanoids, saponins and tannins etc.) which are present in the encapsulated T. arjuna not onlywithstand the processing conditions but also are effectively released in the intestine and showtheireffects, such ashypolipidaemic and antioxidant activities, for better treating cardiovascular disease. © 2015 Society of Chemical Industry.en_US
dc.identifier.citationJournal of the Science of Food and Agriculture 2016; 96: 1380–1385en_US
dc.identifier.urihttp://hdl.handle.net/123456789/2356
dc.language.isoenen_US
dc.publisherSociety of Chemical Industryen_US
dc.subjectcardiovascular diseaseen_US
dc.subjecthigh cholesterol dieten_US
dc.subjecthyperlipidaemiaen_US
dc.subjectanti-oxidanten_US
dc.subjectTerminalia arjunaen_US
dc.titleHypolipidaemic and anti-oxidative potential of encapsulated herb (Terminalia arjuna) added vanilla chocolatemilk in high cholesterol fed ratsen_US
dc.typeArticleen_US
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