Bioactive substances from aquatic sources
Bioactive substances from aquatic sources
Date
2005
Authors
Mathew, S.
Journal Title
Journal ISSN
Volume Title
Publisher
Central Institute of Fisheries Technology
Abstract
Natural products have long been used as foods, fragrances, pigments, insecticides, medicines, etc. Due to their easy accessibility, terrestrial plants have served as the major source of medicinally useful products, especially for traditional or folk medicine. About 25% of all pharmaceutical sales are drugs derived from natural plant products and an additional 12% are from microbial source. The marine environment covers a wide thermal range (from the below freezing temperatures in Antarctic waters to about 350°C in deep hydrothermal vents), pressure range (1-1000 atm), nutrient range (oligotrophic to eutrophic) and it has wide ranging photic and non-photic zones. This extensive variability has facilitated extensive speciation at all phylogenetic levels, from microorganisms to mammals. Despite the fact that the biodiversity in the marine environment far exceeds that of the terrestrial environment, research into the use of
marine natural products as pharmaceutical agents is still in its infancy. This may be due to the lack of ethno-medical history and the difficulties involved in the collection of
marine organisms. But with the development of new techniques, it is possible to collect marine samples and during the past decade, over 5000 novel compounds have been isolated from marine sources.
Description
Keywords
Bioactive substances, aquatic sources
Citation
In Winter School Manual on "Modern techniques for the analysis of fish fish products", organised by the Biochemistry & Nutrition Division of CIFT, Cochin from 19th October to 8th November 2005, 233-242