Carrageenan, a marine sulphated polysaccharide, chemical modifications and anti-viral prospects - Review
Carrageenan, a marine sulphated polysaccharide, chemical modifications and anti-viral prospects - Review
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Date
2022
Authors
P. Amruth
R. Gopika
M. Rosemol Jacob
P Akshay
Preethy Treesa Paul
R. Anandan
Suseela Mathew
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Publisher
International Journal of Chemistry, Material and Environmental Research (IJCMER)
Abstract
Marine realm constitutes diverse resource of bioactive compounds with significant bioactivity. Sulfated polysaccharides from seaweeds such as carrageenanare reported to pose excellent rheological properties. Despite thewide spectrum of usage as additives in the food, cosmetics and pharmaceutical industry, they acquire great developmental prospects in the area of virology. Modulation of structural characteristic of carrageenan have demonstrated remarkable rheological and chemical properties. This review focus on the modulation of structural characteristics of carrageenan with recent insights on enhancement of anti-viral property which gains significance for their application in the area of virology. Presently, there exists scant information on the pharmacology of carrageenan. Therefore, extensive research is required to explore them for the formulation of effective and safe drugs to combat the existing ailments and several novel diseases.Sulfated polysaccharides including carrageenan demonstrate a number of biological activities including antiviral properties.From the reviewed literature, it is concluded that chemical modulation of carrageenan structural characteristichasmanipulated its rheological and chemical properties and are found effective against several group of viruses including influenza A virus, human immunodeficiency virus and numerous others. The current mini review presents the anti-viral prospectives of carrageenan and induces insights to develop effective medication against novel viruses.
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Research Subject Categories::MEDICINE::Chemistry::Biochemistry