Peer Reviewed Journal Articles (Inter.) (B&N)
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- ItemNanoencapsulation in low-molecular-weight chitosan improves in vivo antioxidant potential of black carrot anthocyanin(Wiley, 2021-03-01)Anthocyanins are flavonoids that are potential antioxidant, anti-inflammatory, anti-obesity, and anticarcinogenic nutraceutical ingredients. However, low chemical stability and low bioavailability limit the use of anthocyanins in food. Nanoencapsulation using biopolymers is a recent successful strategy for stabilization of anthocyanins. This study reports the development, characterization, and antioxidant activity of black carrot anthocyanin-loaded chitosan nanoparticles (ACNPs). RESULTS: The ionic gelation technique yielded the ACNPs. The mean hydrodynamic diameter d and polydispersity index PDI of chitosan nanoparticles and ACNPs were found to be d = 455 nm and PDI = 0.542 respectively for chitosan nanoparticles and d = 274 nm and PDI = 0.376 respectively for ACNPs. The size distribution was bimodal. The surface topography revealed that the ACNPs are spherical and display a coacervate structure. Fourier transforminfrared analysis revealed physicochemical interactions of anthocyanins with chitosan. The loading process could achieve an encapsulation efficiency of 70%. The flow behavior index η of encapsulated ACNPs samples revealed Newtonian and shear thickening characteristics. There was a marginal reduction in the in vitro antioxidant potential of anthocyanins after nanoencapsulation, as evidenced from 2,2-diphenyl-1-picrylhydrazyl, ferric reducing antioxidant power, and 2,20-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) assays. Interestingly, the in vivo antioxidant potential of anthocyanins improved following nanoencapsulation, as observed in the serum antioxidant assays.
- ItemIn vivo anti-lipidemic and antioxidant potential of collagen peptides obtained from great hammerhead shark skin waste(Springer, 2021-05-16)The aim of the present study was to evaluate the ability of fish collagen peptides (FCP) derived from the skin of great hammerhead shark (Sphyrna mokarran) in attenuating the high fat diet-alcohol induced hyperlipidemia. The oral supplementation of FCP in high fat dietalcohol fed experimental rats confirmed the regulation of body weight to normal level. The FCP treated group revealed the efficient lipid lowering ability by enhancing the cholesterol metabolism. Western blot analysis of the lipid metabolic enzymes revealed that the oral-intake of FCP has down-regulated the expression levels of fatty acid synthase and 3-Hydroxy-3-methylglutaryl-CoA reductase (HMGCR). Simultaneously, the expression levels of Lecithin–cholesterol acyltransferase (LCAT) in liver was up-regulated. Histopathology analysis of liver tissues demonstrated that the FCP treated group maintained normal liver parenchyma with moderate inflammatory infiltration, whereas the statin treated group developed centrilobular fibrosis, atrophy of hepatocytes and moderate inflammatory infiltration. Oral dietary supplementation of FCP enhanced the activity levels of both superoxide dismutase and catalase enzymes and, lowered the levels of lipid peroxidation in liver tissues.
- ItemPufferfish poisoning from Arothron stellatus: The first confirmed case in India with exact DNA sequencing-based species identification(Elsevier, 2021-09)A puffer fish poisoning case was reported from the coastal city of Veraval in the Gujarat state of India with patient reporting symptoms of giddiness, vertigo, aphasia and heaviness of head following consumption of cooked fish. Treatment was purely symptomatic and supportive. The patient was discharged from the hospital in a stable condition after 4 days. The suspected fish species was later identified using DNA (Deoxyribonucleic Acid) sequencing as Arothron stellatus with 100% identity.
- ItemTrace-minerals and lipid quality indices in seaweeds growing at Okha, India: A health risk assessment(Elsevier, 2021-07-12)A study was conducted to determine the presence of trace elements and heavy metals in marine macrophytes belonging to chlorophyceae and phaeophyceae collected from Okha, India, the North-eastern Arabian Sea. The result shows there is a mark of difference in the metal content among the seaweeds of different groups.In green seaweeds i.e chlorophyceae the trend of mineral content was Fe>Al>Zn>As>Pb>Cu>Cr and Cd, whereas the trend in phaeophyceae was Fe>Al>Zn>As>Cu>Pb>Cr>Cd. The Hazard Quotient (HQ) and Total Hazard Index (THI) were < 1, the Metal Pollution Index (MPI) were 0.83 (Ulva reticulata) to 7.39 (Padina tetrastromatica) . The result of MPI indicates that there is very-low to low contamination of heavy metals in the seaweeds. The cardiovascular indices of lipid viz. AI (Index of atherogenicity) (0.27-1.0), TI (Index of thrombogenicity) (0.13–0.41) were low and HH (Hypocholesterolomic/Hypercholesterolemic) (2.38– 4.15)& UI (Unsaturation Index) (183.09-236) was high. The overall result indicates that the seaweed studied can be recommended for consumptions.
- ItemExtraction and Characterization of Myofibrillar Proteins from Different Meat Sources: A Comparative Study(Elsevier, 2021-04-07)In the present study, myofibrillar proteins were extracted from the meat proteins of beef, lamb, chicken, tuna and emperor fish using non-denaturation method, and their physico-chemical and rheological properties were assessed. The myofibrillar proteins of beef, emperor and lamb samples had higher percentage of protein extractability than tuna and chicken samples. The tuna sample showed significantly higher bound bromophenol blue (BPB) value while lamb samples showed lower value ( P < 0.05). The myofibrillar protein of chicken sample was found to have more ionic and hydrogen bonds than all other myofibrillar samples. The disulphide bonds in tuna and lamb myofibrillar protein samples were significantly higher than other three samples ( P < 0.05). The myofibrillar protein samples showed major bands myosin heavy chain, 𝛼-actinin, desimin, actin, troponin, tropomyosin and myosin light chain with wider molecular weight distribution in the range of 20–200 ku. The myofibrillar proteins exhibited Newtonian and shear thickening nature behaviour at lower protein concentration (1 mg/mL) as revealed by flow profile and visco-elastic analysis using rheometer.