Organophosphorus insecticide, methyl parathion toxicity in labeo rohita

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dc.contributor.authorSivaperumal, P.
dc.contributor.authorSankar, T.V.
dc.date.accessioned2014-06-13T07:22:34Z
dc.date.available2014-06-13T07:22:34Z
dc.date.issued2013
dc.description.abstractThe effects of three sublethal concentrations of Methyl Parathion (MP) toxicity were evaluated in freshwater fish Labeo rohita. Lipid peroxidation (LPO) and antioxidant enzymes viz., superoxide dismutase (SOD, EC 1.15.1.1), catalase (CAT, EC 1.11.1.6), glutathione peroxidase (GPx, EC 1.11.1.9), glutathione S-transferase (GST, EC 2.5.1.18) and total reduced glutathione (GSH EC 1.6.4.2) were estimated in liver and the neurotoxic effects were investigated by the determination of acetylcholinesterase (AChE, EC 3.1.1.7) activities in brain of Labeo rohita of size 75 ± 6 g at sub lethal exposure. The exposure to MP at 1.0 mg L-1 increased LPO by twofold and in 45 days almost five-fold increase was observed when compared to control. SOD activity increased by three-fold (0.5 mg L-1) and six-fold (1 mg L-1) at sub lethal exposure of MP. The AChE activity decreased with increase in the concentration of MP. The results show that changes in antioxidant enzymes system and inhibition of AChE activity can be used as biomarkers of exposure to MP in aquatic ecosystemsen_US
dc.identifier.citationFishery Technology 2013: 50 (3), 231-236en_US
dc.identifier.urihttp://hdl.handle.net/123456789/1736
dc.language.isoenen_US
dc.publisherSociety of Fisheries Technologists (India)en_US
dc.subjectMethyl parathionen_US
dc.subjectLabeo rohitaen_US
dc.subjectoxidative stressen_US
dc.subjectantioxidant enzymesen_US
dc.subjectacetylcholinesteraseen_US
dc.titleOrganophosphorus insecticide, methyl parathion toxicity in labeo rohitaen_US
dc.typeArticleen_US
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