Peer Reviewed Journal Articles (National) (QAM)
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Browsing Peer Reviewed Journal Articles (National) (QAM) by Author "Anandan, R."
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- ItemBiochemical studies on the cardioprotective effect of squalene against Isoprenaline-induced myocardial infarction in rats(Society of Fisheries Technologists (India), Cochin, 2009) Farvin, K.H.S.; Anandan, R.; Kumar, S.H.S.; Mathew, S.; Sankar, T.V.; Nair, P.G.V.This study was designed to examine the cardioprotective effect of squalene against isoprenaline-induced myocardial infarction in male albino rats. Levels of diagnostic markers [troponin T, homocysteine], lipoproteins [apolipoprotein Al, apolipoprotein B, lipoprotein (a)] (in plasma), total cholesterol, lipid peroxides (in plasma and heart tissue), and endogenous non-enzymatic antioxidants [vitamin C and vitamin EJ (in heart tissue) were determined. Supplementation of squalene at 2% level along with feed for 45 days significantly prevented the isoprenaline-induced elevation in the diagnostic markers in plasma of experimental group of rats. It exerted an antilipidemic action against isoprenaline-induced hypercholesterolemia by maintaining the levels of cholesterol and lipoprotein components at near normalcy. Squalene supplementation exhibited an antioxidant effect against isoprenaline-induced myocardial infarction by blocking the induction of lipid peroxidation. A tendency to prevent the isoprenaline induced reduction in the non-enzymatic antioxidants such as vitamin E and C was also observed. The results of the present study indicate that the cardioprotective effect of squalene might be ascribable to its antilipidemic, antioxidant and membrane stabilizing properties.
- ItemNutritional quality evaluation of feeds developed from secondary raw material from fish processing industry(Society of Fisheries Technologists (India), Cochin, 2019) Zynudheen, A.A.; Nambiar, M.M.L.; Ravindran, R.; Anandan, R.; Ninan, G.Fresh head waste of sardine, threadfin bream, anchovy and tilapia was converted into fish meal after cooking and pressing. Whole sardine was used as control sample. Quality analysis of the prepared meal revealed that the protein content was lower for sardine waste (43.1%) and higher for tilapia (62.3%). The fish meal prepared was used as the protein source for preparing feed along with other ingredients. Isoprotenous feed prepared was administered in Wistar strain male albino rats for a period of 31 days and Feed Intake (FI) Protein Efficiency Ratio (PER) and Feed Conversion Ratio (FCR) was estimated. Feed intake was more in threadfin bream waste feed and anchovy waste feed (135.1 g/31 days) which was significantly different from other feeds. The acceptance of feed developed from the waste of fish shows more or less similar to control feed indicating that the waste can be utilized for the development of feed for different animals thereby resolving the problem of environmental pollution.