Peer Reviewed Journal Articles (Inter.) (FP)
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Browsing Peer Reviewed Journal Articles (Inter.) (FP) by Author "Anandan, R."
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- ItemEffect of chittosan supplimentation on antitubercular drugs-induced hepatotoxicity in rats(Elseviar, 2006) Santhosh, S.; Sini, T.K.; Anandan, R.; Mathew, P.T.We have studied the protective effect of chitosan on isoniazid- and rifampicin-induced hepatotoxicity with respect to the changesin the levels of diagnostic marker enzymes (in serum), lipid components and lipid peroxidation (in serum and liver). The oraladministration of antitubercular drugs caused a significant elevation in the levels of diagnostic marker enzymes and cholesterol, triglycerides, free fatty acids and lipid peroxidation in serum and liver of experimental rats. There was a slight decline in thelevel of phospholipids in liver tissue also observed.Co-administration of chitosan significantly prevented the antitubercular drugsinducedelevation in the levels of serum diagnostic marker enzymes (alanine amino transferase, aspartate amino transferase, lactatedehydrogenase, acid phosphatase and alkaline phosphatase) in experimental groups of rats. It exerted a significant antilipidemiceffect against isoniazid- and rifampicin-induced hepatitis by maintaining the levels cholesterol, triglycerides, free fatty acids and phospholipids in serum and liver at near normalcy. A tendency to prevent the isoniazid- and rifampicin-induced lipid peroxidationwas also observed. The results of the present study indicated that the hepatoprotective effect of chitosan might be ascribable to itsantilipidemic effect and/or antioxidant property
- ItemEffect of essential oil and aqueous extract of ginger (Zingiber Officinale) on oxidative stability of fish oil-in-water emulsion(OMICS International, 2015) Jeyakumari, A.; Venkateshwarlu, G.; Choukse, M.K.; Anandan, R.Fish oil-in-water emulsion (5%) was prepared with essential oil and aqueous extract of ginger (Zingiber officinale) rhizome and their oxidative stability was examined. Antioxidant activities of essential oil and aqueous extract of ginger revealed total phenolic was high in essential oil (130.70 mg Catechol equivalents /l) than aqueous extract (24.38 mg Catechol equivalents /l) at 5% concentration. Chemical composition of Ginger (Zingiber officinale) essential oil was determined by GC-MS analyses showed Ginger essential oil contained, zingiberene (27.45 ± 0.30%), copaene (13.82 ± 0.06%), camphane (11.10 ± 0.16%), geranial (10.98 ± 0.10), as the major compounds. Oxidative stability test (thiobarbituric acid reactive substances) revealed that, In oil-in water emulsion, essential oil (1%) and aqueous extract (20%) together acted more significantly (p<0.05) against lipid oxidation (9.21 m mol O2/kg and 3.02 mg malonaldehyde/l) than control (21.33 m mol O2/kg and 4.31 mg malonaldehyde/l). Results from the study indicate that both essential oil and aqueous extract of ginger can be utilized together as a source of natural antioxidant to inhibitive action on fish oil-in-water emulsion.
- ItemQuality evaluation of fish soup powder supplemented with carrageenan(2016) Jeyakumari, A.; Christin Joseph; Zynudheen, A.A.; Anandan, R.Carrageenans are widely utilized in food industry because of their physical and functional properties. In the present study, carrageenan was extracted from red seaweed and it was tested for the possibility for making healthy and nutritious fish soup for human consumption. The spray dried carrageenan powder had a protein, ash content of 12.12%, 34.53% respectively. Fish soup powder was prepared with the addition of 5% carrageenan powder and their nutritional properties were evaluated. Fish soup powder contained corn flour was served as control. Results suggested that fish soup powder can be prepared with the supplementation of carrageenan at 5% level without affecting consistency and flavor characteristics of soup and thereby increase the nutritional value of healthy soup for human consumption.