FT Vol.52(4)
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Browsing FT Vol.52(4) by Subject "liver oil"
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- ItemProtective Effects of Echinorhinus brucus Liver Oil against Induced Inflammation and Ulceration in Rats(Central Institute of Fisheries Technology, Cochin, India, 2015) Vishnu, K.V.; Ajeeshkumar, K.K.; Asha, K.K.; Remyakumari, K.R.; Ganesan, B.; Anandan, R.; Chatterjee, N.S.; Suseela MathewAnti-inflammatory and anti-ulcer activities of Bramble shark (Echinorhinus brucus) liver oil were examined in rats. The oil showed significant proportion of n-3 polyunsaturated fatty acids (PUFAs), the percentages of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) being 16 and 18% respectively. The study also revealed that liver oil had a very favourable n3:n6 ratio of 4.7. Oral administration of shark liver oil at 1g kg-1 concentration significantly attenuated the formalin-induced paw edema in experimental rats. It exerted potent anti-ulcer effect against acid-ethanol mixturemediated lesion formation in the rat gastric mucosa.