Resistance of Escherichia coli and Salmonella isolated from marine and freshwater fishes towards Carbapenems

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dc.contributor.authorRao, M.B.
dc.contributor.authorMurthy, L.N.
dc.contributor.authorJesmi, D.
dc.contributor.authorPrasad, M.M.
dc.date.accessioned2014-07-30T08:24:14Z
dc.date.available2014-07-30T08:24:14Z
dc.date.issued2014
dc.description.abstractThe carbapenems are beta-lactam antimicrobial agents with an exceptionally broad spectrum of activity and are active against most Enterobacteriaceae including those that produce ampC b-lactamase. Resistance to carbapenems, especially carbapenems-resistant-Enterobacteriaceae (CRE) is a serious issue worldwide as it is extremely difficult to combat bacteria resistant to carbapenems. Fifty two isolates of Escherichia coli and twelve isolates of Salmonella (invA and stn gene positive) isolated from marine fish and freshwater fish were tested for their susceptibility to carbapenems namely meropenem, imipenem and ertapenem. A low percentage (3.9%) of E.coli showed resistance to meropenem, while 11.5 & 17% of E.coli and 8.3 & 25% of Salmonella showed intermediate sensitivity to meropenem and ertapenem, respectively. However, 100% of E. coli and Salmonella were sensitive to imipenem. Importantly, meropenem resistant E.coli was also found to be resistant to other antibiotics such as ciprofloxacin, gentamicin, nalidixic acid, norfloxacin and tetracycline. The results indicate that carbapenem resistance in E. coli and Salmonella isolated from fish was marginal but nevertheless needs continuous monitoring.en_US
dc.identifier.citationFishery Technology 2014: 51(3), 207-212en_US
dc.identifier.urihttp://hdl.handle.net/123456789/1807
dc.language.isoenen_US
dc.publisherSociety of Fisheries Technologists (India), Cochin, Indiaen_US
dc.subjectCarbapenemsen_US
dc.subjectmeropenemen_US
dc.subjectertapenemen_US
dc.subjectimipenemen_US
dc.subjectEscherichia colien_US
dc.subjectSalmonellaen_US
dc.subjectantibiotic resistanceen_US
dc.titleResistance of Escherichia coli and Salmonella isolated from marine and freshwater fishes towards Carbapenemsen_US
dc.typeArticleen_US
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FT Vol.51(3)