Anti diabetic and anti hyperlipidemic activities of different extracts of ailanthus malabarica stem bark in alloxan induced diabetic rats

Simple item page
dc.contributor.authorLouis, T.
dc.contributor.authorYuvaraj, P.
dc.contributor.authorMadhavachandran, V.
dc.contributor.authorAnandan, R.
dc.date.accessioned2016-07-05T06:16:43Z
dc.date.available2016-07-05T06:16:43Z
dc.date.issued2015
dc.description.abstractTo evaluate the anti diabetic and anti hyperlipidemic activities of different extracts of Ailanthus malabarica stem bark in alloxan induced diabetic rats. Different extracts (hexane, ethanol and water, 50 mg/kg) of A. malabarica stem bark were administered to alloxan-induced diabetic rats for 21 days and blood glucose levels of the diabetic rats were monitored at one week intervals. Lipid profiles of the treated diabetic rats were determined after the period of treatment. Treatment of alloxan-induced diabetic rats with ethanol extract of A. malabarica stem bark caused a significant (P<0.05) reduction in fasting blood glucose levels of the diabetic rats in 21 days treatment. The ethanol extract showed a comparable action with the reference drug, glibenclamide. The ethanol extract exerted a significant reduction in the levels of serum total cholesterol, triglycerides, LDL, VLDL and phospholipids, and increase in HDL levels of the diabetic rats. However, water and hexane extract of A. malabarica stem bark did not show any such beneficial effects. . These results suggest that the ethanol extract of A. malabarica stem bark possesses anti diabetic effect on alloxan induced diabetic rats and this justifies its usage in ethno medicine and can be exploited in the management of diabetes.en_US
dc.identifier.citationInternational Journal of Biological & Pharmaceutical Research 2015: 6(5) 327-331en_US
dc.identifier.urihttp://hdl.handle.net/123456789/2251
dc.language.isoenen_US
dc.publisherPharma Intelligenceen_US
dc.subjectantidiabeticen_US
dc.subjectantihyperlipidimicen_US
dc.subjectailanthus malabaricaen_US
dc.subjectstem barken_US
dc.titleAnti diabetic and anti hyperlipidemic activities of different extracts of ailanthus malabarica stem bark in alloxan induced diabetic ratsen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Anti diabetic and anti hyperlipidemic activities of different extracts of ailanthus malabarica stem bark in alloxan induced diabetic rats.pdf
Size:
275.07 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Peer Reviewed Journal Articles (Inter.) (B&N)