Biochemical characterization of liver oil of echinorhinus brucus (bramble shark) and its cytotoxic effect on neuroblastoma cell lines (SHSY-5Y)

Simple item page
dc.contributor.authorVishnu, K.V.
dc.contributor.authorAjeeshkumar, K.K.
dc.contributor.authorChatterjee, N.S.
dc.contributor.authorSuvanish Kumar
dc.contributor.authorShyni, K.
dc.contributor.authorJayarani, R.
dc.contributor.authorSuseela Mathew
dc.date.accessioned2018-01-11T06:12:00Z
dc.date.available2018-01-11T06:12:00Z
dc.date.issued2016
dc.description.abstractThe objective of the present study was to characterize the liver oil extracted from the deep sea shark, Echinorhinus brucus, caught from Central Indian Ocean and to evaluate its cytotoxic effect on neuroblastoma cell line (SHSY-5Y). Characterization of liver oil of Echinorhinus brucus revealed the presence of palmitic acid (15%), oleic acid (12%), stearic acid (8%), docosahexaenoic acid (DHA) (18%), and eicosapentaenoic acid (EPA) (16%). It was also found to be a good source of squalene (38.5%) and fat soluble vitamins such as A, D, and K (vitamin A: 17.08mg/100 g of oil, vitamin D: 15.04mg/100 g oil, and vitamin K: 11.45mg/100 g oil). Since it was found to be rich in essential fatty acids, fat soluble vitamins, and squalene, it can be considered as better dietary supplement.The oil of Echinorhinus brucus also showed high in vitro cytotoxic effect against the human neuroblastoma cell line (SHSY-5Y) and the IC50 value laid between 35 and 45 ng.en_US
dc.identifier.citationScientifica, Article ID 6294030, 6 pages http://dx.doi.org/10.1155/2016/6294030en_US
dc.identifier.urihttp://hdl.handle.net/123456789/3329
dc.language.isoenen_US
dc.titleBiochemical characterization of liver oil of echinorhinus brucus (bramble shark) and its cytotoxic effect on neuroblastoma cell lines (SHSY-5Y)en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Biochemical Characterization of Liver Oil.pdf
Size:
745.68 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Peer Reviewed Journal Articles (Inter.) (B&N)