Effect of rhizophora root extracts on wound healing and yeast-induced pyrexia in rats
Effect of rhizophora root extracts on wound healing and yeast-induced pyrexia in rats
Date
2012
Authors
Mathew, M.
Xavier, K.A.M.
Mathew, S.
Asha, K.K.
Kumar, K.A.
Journal Title
Journal ISSN
Volume Title
Publisher
Society of Fisheries Technologists(India),Cochin
Abstract
Mangrove plants are part of tropical marine ecosystems of coastal regions of Kerala, India and their parts are widely used as folklore medicines. Root extracts of Rhizophora mucronata and Rhizophora apiculata from Cochin backwater area, Kerala, India were screened for antipyretic and wound healing properties. Methanolic aqueous root extracts of R. mucronata and R. apiculata were tested at 460 and 535 mg kg super(-1) concentrations respectively, in male albino rats. In both cases, bioactivities were compared with that of standard drug and a control group. Among the two species analyzed, maximum activity was observed in the methanolic root extracts of R. apiculata followed by R. mucronata. It is postulated that antipyretic and wound healing effects are caused by inhibition of prostaglandin synthesis and decrease in the cytokine levels. Phytochemical screening of residues revealed the presence of carbohydrates, alkaloids, tannins, flavonoids, saponins and glycosides, which may account for the observed pharmaceutical effects in the Rhizophora species studied.
Description
Keywords
Antipyretic, excision wound, mangroves
Citation
Fishery Technology 2012: 49(2), 161-166