Effect of rhizophora root extracts on wound healing and yeast-induced pyrexia in rats

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dc.contributor.authorMathew, M.
dc.contributor.authorXavier, K.A.M.
dc.contributor.authorMathew, S.
dc.contributor.authorAsha, K.K.
dc.contributor.authorKumar, K.A.
dc.date.accessioned2013-12-31T09:50:20Z
dc.date.available2013-12-31T09:50:20Z
dc.date.issued2012
dc.description.abstractMangrove plants are part of tropical marine ecosystems of coastal regions of Kerala, India and their parts are widely used as folklore medicines. Root extracts of Rhizophora mucronata and Rhizophora apiculata from Cochin backwater area, Kerala, India were screened for antipyretic and wound healing properties. Methanolic aqueous root extracts of R. mucronata and R. apiculata were tested at 460 and 535 mg kg super(-1) concentrations respectively, in male albino rats. In both cases, bioactivities were compared with that of standard drug and a control group. Among the two species analyzed, maximum activity was observed in the methanolic root extracts of R. apiculata followed by R. mucronata. It is postulated that antipyretic and wound healing effects are caused by inhibition of prostaglandin synthesis and decrease in the cytokine levels. Phytochemical screening of residues revealed the presence of carbohydrates, alkaloids, tannins, flavonoids, saponins and glycosides, which may account for the observed pharmaceutical effects in the Rhizophora species studied.en_US
dc.identifier.citationFishery Technology 2012: 49(2), 161-166en_US
dc.identifier.urihttp://hdl.handle.net/123456789/1207
dc.language.isoenen_US
dc.publisherSociety of Fisheries Technologists(India),Cochinen_US
dc.subjectAntipyreticen_US
dc.subjectexcision wounden_US
dc.subjectmangrovesen_US
dc.titleEffect of rhizophora root extracts on wound healing and yeast-induced pyrexia in ratsen_US
dc.typeArticleen_US
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